Heartburn Remedies

🔥+ Heartburn Remedies 05 Jun 2020 Epithelial cells remove excess hydrogen ions (H+) via membrane transport systems and have tight junctions, which prevent back diffusion of H+ ions. Mucosal ...

Heartburn Remedies Did You Know? The most common symptom of acid reflux and GERD is heartburn. When heartburn happens regularly two or more times a week, ...

Seasoned Salt Acid Reflux

Your source for the latest research news
the 1 last update 05 Jun 2020 advertisementadvertisement
Follow all of ScienceDaily''s risk of developing stomach cancer. But a substantial proportion of those in whom treatment is successful still go on to develop the disease, the third leading cause of cancer death in the world.

Previously published research has found an association between PPI use and heightened stomach cancer risk, but it was unable to factor in the potential role of H pylori itself, so undermining the strength of the findings.

To try and get round this, the researchers compared the use of PPIs with another type of drug used to dampen down acid production called histamine H2 receptor antagonists (H2 blockers) in 63,397 adults treated with triple therapy -- a combination of a PPI and two antibiotics to the 1 last update 05 Jun 2020 kill off H pylori over 7 days -- between 2003 and 2012.To try and get round this, the researchers compared the use of PPIs with another type of drug used to dampen down acid production called histamine H2 receptor antagonists (H2 blockers) in 63,397 adults treated with triple therapy -- a combination of a PPI and two antibiotics to kill off H pylori over 7 days -- between 2003 and 2012.

They were subsequently monitored until they either developed stomach cancer, died, or the study ended (end of December 2015), whichever came first. The average monitoring period lasted 7.5 years.


During this time, 3271 (5%) people took PPIs for an average of nearly three years; and 21,729 took H2 blockers.

Heartburn Remedies Acid Reflux (☑ Tests) | Heartburn Remedies Herbshow to Heartburn Remedies for In all, 153 (0.24%) people developed stomach cancer after triple therapy. None tested positive for H pylori at the time, but all had long standing gastritis (inflammation of the stomach lining).

Taking PPIs was associated with a more than doubling (2.44) in the risk of developing stomach cancer, while taking H2 blockers was not associated with any such heightened risk.

The average time between triple therapy and the development of stomach cancer was just under 5 years.

Heartburn Remedies Side Effects (🔥 Acid Reflux) | Heartburn Remedies Breakfast Forhow to Heartburn Remedies for More frequent use was associated with greater risk, with daily use linked to a more than quadrupling in risk (4.55) compared with weekly use.

And the longer PPIs were used, the greater was the risk of developing stomach cancer, rising to 5-fold after more than a year, to more than 6-fold after two or more years, and to more than 8-fold after three or more years.

This is an observational study, so no firm conclusions can be drawn about cause and effect, and PPIs are generally considered safe, say the researchers.

But recent research has linked their long term use to various unwanted effects, including pneumonia, heart attack, and bone fracture, they point out, adding that PPIs are known to stimulate the production of gastrin, a powerful growth factor.

The "" in the use of PPIs and stomach cancer for 1 last update 05 Jun 2020 risk, prompt them to suggest that doctors ""The "" in the use of PPIs and stomach cancer risk, prompt them to suggest that doctors ""

make a difference: sponsored opportunity

Story Source:

Materials provided by BMJ. Note: Content may be edited for style and length.

Journal Reference:

  1. Ka Shing Cheung, Esther W Chan, Angel Y S Wong, Lijia Chen, Ian C K Wong, Wai Keung Leung. Long-term proton pump inhibitors and risk of gastric cancer development after treatment forHelicobacter pylori: a population-based study. Gut, 2017; gutjnl-2017-314605 DOI: 10.1136/gutjnl-2017-314605

Cite This Page:

BMJ. "" ScienceDaily. ScienceDaily, 31 October 2017. <www.sciencedaily.com/releases/2017/10/171031202203.htm>.
BMJ. (2017, October 31). Long-term use of drugs to curb acid reflux linked to doubling in stomach cancer risk: Risk rose in tandem with dose and duration of proton pump inhibitor (PPI) treatment. ScienceDaily. Retrieved May 6, 2020 from www.sciencedaily.com/releases/2017/10/171031202203.htm
BMJ. "" ScienceDaily. www.sciencedaily.com/releases/2017/10/171031202203.htm (accessed May 6, 2020).



Acid Suppression Medications Linked to Serious Gastrointestinal Infections
Heartburn Remedies Help Relieve (👍 Acidity) | Heartburn Remedies 7 Foods That Causehow to Heartburn Remedies for Jan. 5, 2017 — In a population-based study from Scotland, use of commonly-prescribed acid suppression medications such as proton pump inhibitors (PPIs) was linked with an increased risk of intestinal infections ... read more
Popular Heartburn Medication May Increase Ischemic Stroke Risk
Nov. 15, 2016 — A popular group of antacids known as proton pump inhibitors, or PPIs, used to reduce stomach acid and treat heartburn may increase the risk of ischemic stroke, according to preliminary ... read more
Proton Pump Inhibitors Associated With Risk of Chronic Kidney Disease
Jan. 11, 2016 — Proton pump inhibitors (PPIs), which are commonly used drugs to reduce acid in the stomach, appear to be associated with an increased risk of chronic kidney disease but more research is needed to ... read more
Acid Reflux Medications May Increase Kidney Disease Risk
for 1 last update 05 Jun 2020 Oct. 27, 2015 —Oct. 27, 2015 — Certain medications commonly used to treat heartburn and acid reflux may have damaging effects on the kidneys, according to two new studies. The drugs, proton pump inhibitors (PPIs), are among the ... Heartburn Remedies Home Remedies For (☑ List Of) | Heartburn Remedies Besthow to Heartburn Remedies for read more

Below are relevant articles that may interest you. ScienceDaily shares links with scholarly publications in the TrendMD network and earns revenue from third-party advertisers, where indicated.
  Print   Email   Share

Heartburn Remedies 10 Drinks To Avoid (⭐️ Cause Acid Reflux) | Heartburn Remedies Foods That Fight Hearbturnhow to Heartburn Remedies for advertisement

Most Popular
this week

The Best Material for Homemade Face Masks May Be a Combination of Two Fabrics
COVID-19 Coronavirus Epidemic Has a Natural Origin
Heartburn Remedies Diet (⭐️ Home Remedies) | Heartburn Remedies How To Naturally Treathow to Heartburn Remedies for Loss of Smell and Taste Validated as COVID-19 Symptoms in Patients With High Recovery Rate
Eyes Send an Unexpected Signal to the Brain
Scientists Regenerate Neurons in Mice With Spinal Cord Injury and Optic Nerve Damage
Heartburn Remedies To Avoid (🔴 Home Remedies For) | Heartburn Remedies Symptomshow to Heartburn Remedies for Link Between Obesity and Sleep Loss
Boy or Girl? It''s Genes
Some COVID-19 Patients Still Have Coronavirus After Symptoms Disappear
Wearing Surgical Masks in Public Could Help Slow COVID-19 Pandemic''s Why
Offspring May Inherit Legacy of Their Father''s
  • Autism
  • Depression
  • Headaches
  • Intelligence
  • Psychology
  • Relationships
  • Schizophrenia
  • ... more topics
  • Living Well
  • Tech
  • Enviro
  • Society
  • Quirky