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The Sidney Kimmel Comprehensive Cancer Center

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Barrett’s esophagus is a condition that can arise from acid reflux and increase your risk of developing esophageal cancer. Esophageal cancer occurs inside the esophagus, which is the tube in the throat that moves food from the mouth to the stomach.

Barrett’s esophagus occurs when the cells in the lining of your esophagus are damaged from acid reflux. If those cells develop abnormally, this can result in dysplasia, a pre-cancerous condition that can lead to esophageal cancer if left untreated. 

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Esophageal Cancer: What You Need to Know

  • Barrett’s esophagus is a complication of gastrointestinal reflux disease (GERD). An estimated 10-15 percent of patients with GERD will develop Barrett’s esophagus.
  • Approximately one in 860 Barrett’s esophagus patients will develop esophageal cancer, meaning the risk is statistically low.
  • Barrett’s esophagus is twice as common in men than in women, and usually targets Caucasian men over the age of 50 who have had heartburn for many years.
  • Barrett’s esophagus, while not reversible, is treatable and should be monitored closely by a trained specialist to minimize your risk of developing cancer.

Patient Resources

Learn more about Barrett’s esophagus in our Health Library.

Read our FAQs about Barrett’s esophagus.

Read a more in-depth article about Barrett’s esophagus, written by Johns Hopkins gastroenterologists, which details an anatomical description of the causes of Barrett’s Esophagus.

Read our frequently asked questions about esophageal cancer.

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Why choose Johns Hopkins for monitoring Barrett’s Esophagus?

Our Physicians

At Johns Hopkins, our gastroenterologists and esophageal cancer specialists work together to monitor patients with Barrett’s Esophagus. We provide the full range of diagnostic tests and evaluation, ensuring early detection and proactive treatment of esophageal cancer.


Our Treatments

Our doctors are the world leaders in effective treatments and procedures for Barrett’s esophagus, including cryoablative therapy. This treatment uses freezing technology for elimination of Barrett’s esophagus and less pain compared to other technologies. Learn more about our pioneering research on endoscopic cryotherapy.

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Early esophageal cancer can be removed and cured using a minimally invasive non-surgical outpatient endoscopic technique called endoscopic mucosal resection (EMR).

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Our team is dedicated to treating patients with Barrett’s Esophagus and educating them about the risk of esophageal cancer and prevention strategies. We provide expert care and compassionate support during your entire course of treatment at Hopkins. Learn more about our patient support services.

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Traveling for Care?

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Second Opinion

Request a second opinion before esophageal cancer treatment. 

Frequently Asked Questions

Experts answer common questions after an esophageal cancer diagnosis. 

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